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Chicken and Spinach Casserole with Cream Cheese

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This Chicken and Spinach Casserole with Cream Cheese is the ultimate comfort food, combining tender chicken, a creamy spinach sauce, and a melted cheese topping. Perfect for weeknight dinners or impressing guests, this dish is simple to prepare yet incredibly indulgent. With rich cream cheese, Parmesan, and mozzarella, it offers a creamy, savory flavor in every bite. Whether you’re following a low-carb diet, craving something spicy, or looking for a vegetarian alternative, this casserole is versatile and delicious.

  • Total Time: 45 minutes
  • Yield: 4 servings

Ingredients

4 boneless, skinless chicken breasts

2 tablespoons olive oil

1 teaspoon garlic powder

1 teaspoon onion powder

1/2 teaspoon salt

1/4 teaspoon black pepper

1/2 cup cream cheese, softened

1/2 cup sour cream

1/2 cup grated Parmesan cheese

1 cup shredded mozzarella cheese

3 cups fresh spinach, chopped

1/2 cup chicken broth

1 tablespoon fresh parsley, chopped (for garnish)

Instructions

  1. Preheat the oven to 375°F (190°C).

  2. Heat olive oil in a large skillet over medium heat. Season the chicken breasts with garlic powder, onion powder, salt, and pepper.

  3. Cook the chicken for 5-7 minutes per side, until golden brown and cooked through. Remove from heat and set aside.

  4. In the same skillet, add cream cheese, sour cream, and chicken broth. Stir and cook over medium heat until the cream cheese is fully melted and the mixture is smooth.

  5. Add the spinach and cook for another 2-3 minutes until wilted.

  6. Stir in grated Parmesan cheese and half of the mozzarella cheese.

  7. Slice the cooked chicken breasts and arrange them in a greased 9×13-inch casserole dish.

  8. Pour the creamy spinach mixture over the chicken and sprinkle the remaining mozzarella cheese on top.

  9. Bake for 20-25 minutes, or until the cheese is bubbly and golden.

  10. Garnish with fresh parsley before serving.

Notes

For a vegetarian version, substitute chicken with tofu or extra vegetables like mushrooms and zucchini.

If you prefer a different flavor, mix in sharp cheddar or Gruyère cheese.

Add red pepper flakes for a spicy kick, or top with hot sauce before baking.

For a low-carb option, use vegetable broth and skip the mozzarella topping.

  • Author: Anna
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Main Course
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 4 servings
  • Calories: 410 kcal